ALTRUISM, EGOISM AND GROUP COHESION IN A LOCAL INTERACTION MODEL

In this paper we have introduced and parameterized the concept of ?group cohesion? in a model of local interaction with a population divided into groups. This allows us to control the level of ?isolation? of these groups: We thus analyze if the degree of group cohesion is relevant to achieve an efficient behaviour and which level would be the best one for this purpose. We are interested in situations where there is a trade off between efficiency and individual incentives. This trade off is stronger when the efficient strategy or norm is strictly dominated, as in the Prisoner?s Dilemma or in some cases of Altruism. In our model we have considered that agents could choose to be Altruist of Egoist, in fact, they behave as in Eshel, Samuelson and Shaked (1998) model.Group Cohesion, Cooperation, Local Interaction, Altruism, Group selection.

TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells

The epithelial-to-mesenchymal transition (EMT) and its reversion (MET) are related to tumor cell dissemination and migration, tumor circulating cell generation, cancer stem cells, chemoresistance, and metastasis formation. To identify chromatin and epigenetic factors possibly involved in the process of EMT, we compare the levels of expression of epigenetic genes in a transformed human breast epithelial cell line (HMEC-RAS) versus a stable clone of the same cell line expressing the EMT master regulator ZEB1 (HMEC-RAS-ZEB1). One of the factors strongly induced in the HMEC-RAS-ZEB1 cells was Transducin beta-like 1 (TBL1), a component of the NCoR complex, which has both corepressor and coactivator activities. We show that TBL1 interacts with ZEB1 and that both factors cooperate to repress the promoter of the epithelial gene E-cadherin (CDH1) and to autoactivate the ZEB1 promoter. Consistent with its central role, TBL1 is required for mesenchymal phenotypes of transformed breast epithelial and breast cancer cell lines of the claudin-low subtype. Importantly, a high expression of the TBL1 gene correlates with poor prognosis and increased proportion of metastasis in breast cancer patients, indicating that the level of TBL1 expression can be used as a prognostic marker.Ministerio de Economía y Competitividad BFU2014-53543-P, BFU2017-85420-RJunta de Andalucía BIO-32

Energy management systems by means of computational intelligence algorithms

This work pretends to take advantage of powerful capabilities of computational intelligence to improve the actual features of modeling, prognosis, diagnosis and optimization of load demand for EMS. This work gives a potent complement to the rising new paradigms about renewable energies, distributed generation, micro-grids and smart grids in general, which are in focusing in the optimization or improving of how the energy is generated and not how the energy is used.Peer ReviewedPostprint (published version

Evaluation of tree-based routing Ethernet

Tree-based Routing (TRE) revisits Tree-based Routing Architecture for Irregular Networks (TRAIN)—a forwarding scheme based on a spanning tree that was extended to use some shortcut links.We propose its adaptation to Ethernet, using a new type of hierarchical Ethernet addresses and a procedure to assign them to bridges. We show that compared to RSTP, TRE offers improved throughput. The impact of transient loops in TRE is lower compared to the application of the classical shortest path routing protocols to Ethernet. Finally, TRE is self-configuring and its forwarding process is simpler and more efficient than in standard Ethernet and shortest path routing proposals.Publicad

Shallow water caprellids (Crustacea: Amphipoda) of Azores and Madeira

The species composition and vertical distribution of caprellids associated to hard bottoms (mainly hydroids and algae) were studied from 0 to 41 m deep in Azores and Madeira. The highest caprellid densities were measured between 0 and 10 m. Caprella acanthifera ‘sensu lato’ and Caprella equilibra Say, 1818 were the dominant species in Azores, while Caprella penantis Leach, 1814 and Pseudoprotella phasma (Montagu, 1804) were more abundant in Madeira. Lateral view figures and taxonomical remarks are provided for each species. Although Macaronesian islands seem to share most of the caprellid species, a detailed morphological and molecular study is necessary to clarify the taxonomical status of some species. Probably, the global diversity of amphipods from Macaronesia is still underestimated.Se estudió la composición de especies y la distribución vertical de los caprélidos asociados a sustrato duro (principalmente hidrozoos y algas) desde los 0 a los 41 m de profundidad en Azores y Madeira. Las mayores densidades de caprélidos se registraron en los primeros 10 m. Caprella acanthifera ‘sensu lato’ y Caprella equilibra Say, 1818 fueron las especies dominantes en Azores, mientras que Ca- prella penantis Leach, 1814 y Pseudoprotella phasma (Montagu, 1804) fueron más abundantes en Madeira. Se incluyen vistas laterales y notas taxonómicas de cada una de las especies. Aunque las islas macaronésicas parecen compartir la mayoría de las especies de caprélidos, se requiere un estudio morfológico y molecular detallado para clarificar el estatus taxonómico de algunas especies. Probablemen- te, la diversidad global de los anfípodos de Macaronesia está aún subestimada.Consejería de Innovación, Ciencia y Empresa de la Junta de Andalucía P05-RNM-369Academy of Scientific Research & Technology (ASRT) Egyptian Government Project No. 5562/201

Hierarchical Up/Down Routing Architecture for Ethernet backbones and campus networks

We describe a new layer two distributed and scalable routing architecture. It uses an automatic hierarchical node identifier assignment mechanism associated to the rapid spanning tree protocol. Enhanced up/down mechanisms are used to prohibit some turns at nodes to break cycles, instead of blocking links like the spannning tree protocol does. The protocol performance is similar or better than other turn prohibition algorithms recently proposed with lower complexity O(Nd) and better scalability. Simulations show that the fraction of prohibited turns over random networks is less than 0.2. The effect of root bridge election on the performance of the protocol is limited both in the random and regular networks studied. The use of hierarchical, tree-descriptive addresses simplifies the routing, and avoids the need of all nodes having a global knowleddge of the network topology. Routing frames through the hierarchical tree at very high speed is possible by progressive decoding of frame destination address, without routing tables or port address learning. Coexistence with standard bridges is achieved using combined devices: bridges that forward the frames having global destination MAC addresses as standard bridges and frames with local MAC frames with the proposed protocol.Publicad

Insight into the dynamics of low temperature dielectric relaxation of ordinary perovskite ferroelectrics

The temperature dependence of the dielectric response of ordinary ferroelectric materials exhibits a frequency-independent anomalous peak as a manifestation of the ferroelectric to paraelectric phase transition. A second anomaly in the permittivity has been reported in different ferroelectric perovskite-type systems at low temperatures, often at cryogenic temperatures. This anomaly manifests as a frequency-dependent local maximum, which exhibits similar characteristics to that observed in relaxor ferroelectrics around their phase transition. The origin of this unexpected behavior is still controversial. In order to clarify this phenomenon, a model-free route solution is developed in this work. Our findings reveal the same critical linear pattern/glass-like freezing behavior previously observed for glass-forming systems. Contrary to current thought, our results suggest that a critical-like dynamic parameterization could provide a more appropriate solution than the conventional Vogel–Fulcher–Tammann equation. The implemented methodology may open a new pathway for analyzing relaxation phenomena in other functional materials like relaxor ferroics.Postprint (published version

The generalized Vogel-Fulcher-Tamman equation for describing the dynamics of relaxor ferroelectrics

Relaxor ferroelectrics (RF) are outstanding materials owing to their extraordinary dielectric, electromechanical, and electro-optical properties. Although their massive applications, they remain to be one of the most puzzling solid-state materials because understanding their structural local order and relaxation dynamics is being a long-term challenge in materials science. The so-called Vogel-Fulcher-Tamman (VFT) relation has been extensively used to parameterize the relaxation dynamics in RF, although no microscopic description has been firmly established for such empirical relation. Here, we show that VFT equation is not always a proper approach for describing the dielectric relaxation in RF. Based on the Adam-Gibbs model and the Grüneisen temperature index, a more general equation to disentangle the relaxation kinetic is proposed. This approach allows to a new formulation for the configurational entropy leading to a local structural heterogeneity related order parameter for RF. A new pathway to disentangle relaxation phenomena in other relaxor ferroics could have opened.Postprint (published version

Computational and analytical studies of the Randic index in Erdös-Rényi models

In this work we perform computational and analytical studies of the Randic´ index R(G) in Erdös–Rényi models G(n, p) characterized by n vertices connected independently with probability p ∈ (0, 1). First, from a detailed scaling analysis, we show that R(G) = {R(G)}/(n/2) scales with the product ξ ≈ np, so we can define three regimes: a regime of mostly isolated vertices when ξ 10 (R(G) ≈ n/2). Then, motivated by the scaling of R(G), we analytically (i) obtain new relations connecting R(G) with other topological indices and characterize graphs which are extremal with respect to the relations obtained and (ii) apply these results in order to obtain inequalities on R(G) for graphs in Erdös–Rényi models.J.A.M.-B. acknowledges financial support from FAPESP (Grant No. 2019/06931-2), Brazil, and PRODEP-SEP (Grant No. 511- 6/2019.-11821), Mexico. J.M.R. and J.M.S. were supported in part by two grants from Ministerio de Economía y Competitividad, Agencia Estatal de Investigación (AEI) and Fondo Europeo de Desarrollo Regional (FEDER) (MTM2016-78227-C2-1-P and MTM2017-90584-REDT), Spain

Working with the HL7 metamodel in a Model Driven Engineering context

HL7 (Health Level 7) International is an organization that defines health information standards. Most HL7 domain information models have been designed according to a proprietary graphic language whose domain models are based on the HL7 metamodel. Many researchers have considered using HL7 in the MDE (Model-Driven Engineering) context. A limitation has been identified: all MDE tools support UML (Unified Modeling Language), which is a standard model language, but most do not support the HL7 proprietary model language. We want to support software engineers without HL7 experience, thus realworld problems would be modeled by them by defining system requirements in UML that are compliant with HL7 domain models transparently. The objective of the present research is to connect HL7 with software analysis using a generic model-based approach. This paper introduces a first approach to an HL7 MDE solution that considers the MIF (Model Interchange Format) metamodel proposed by HL7 by making use of a plug-in developed in the EA (Enterprise Architect) tool.Ministerio de Ciencia e Innovación TIN2013-46928-C3-3-RInstituto de Salud Carlos III PI12/01571Instituto de Salud Carlos III PT13/0006/003